So, in a recent wide-ranging conversation in the gunsmithery at work, the topic of rufies somehow came up. While the very concept of a "date rape drug" is vile and evil, not to mention just being plain dirty pool, one can easily see where something that increases the victim's compliance and suggestibility has a certain dark appeal:
[SCENE: Night club, interior, 2AM.]
Wily Villainess: "Hey, handsome; want a drink?"
Unwitting Victim: "Uh, sure!"
Unwitting Victim: *glug, glug*
Wily Villainess: "So, um... the oil in my car sure needs changing."