I cannot begin to tell you how much this question, which constantly pops up both at work and on internet gun boards, completely grinds me to a halt. (At least they don't ask "What's a good chick gun?" or "What gun do you think a broad could handle?")
At work, I have to be nice and helpful because it's my job and all, and so I display the kind of tolerance with the question that makes Job look like a quitter. On line, however, my patience wore thinner than Kate Moss at least four years ago. My answers to the question "What gun for a woman?" have drifted from the trying-to-be-helpful "What will she be using it for? Which does she like?" to the flippant "I like a snubnose .44 Magnum today," to the dripping-with-sarcasm "You'll want something bigger than a .30-30; we charge when we're wounded."
My 'net friend Kathy is irked even more than I am (if such is possible) by the same question, and has finally written the answer it deserves, right here. (...and gawd don't I wish I'd written it first. Good stuff!)
The advice comes as part of her shiny new web presence at The Cornered Cat, which you need to go scope out, right now. I've been enjoying her posts on the boards for years; I can guar-on-tee you'll like her stuff, too.
(H/T to LawDog.)