Do you live someplace cold? Do you wear gloves in the winter? Have you shot your CCW pistol while wearing those gloves?
At the arctic outdoor range sessions of the last couple weekends, a variety of glove-related maladies were encountered. For instance, it only takes a bit of glove material between the floorplate of a Ruger 22/45 magazine and the butt of the gun to keep the mag from seating fully, resulting in failures to feed. While this isn't such a big deal on a target pistol, it could be unpleasant on a "for real" gun.
Is your gun double-action? If so, how far forward does the trigger have to go to fully reset? Are your gloves thin enough to allow that to happen reliably?
I was shooting my S&W 432PD the weekend before last, and even wearing my thin and ninja-esque supertactical ¡Blackhawk! elite anti-terrorist gloves, things were crowded enough in that J-frame's trigger guard to cause a small amount of glove fabric to bunch atop the trigger during fast double action work, preventing it from resetting. If you've never had this happen before, you'll wonder what's happening as the cylinder continues to rotate normally, only with depressing little *clicks* instead of *bangs*. Yes, Virginia, revolvers malfunction, too.
Gloves didn't make manipulating the dinky HKS J-frame speedloaders any easier, either, but I was a lot better after fifteen or twenty reps than I was at the start of the session, that's for sure.
Do you have CTC Lasergrips on your gun? Awesome, aren't they? Don't work too well with gloves all bunched up in front of the lens, though. Good thing you devote most of your practice to iron sight work!
Got gloves? Wear 'em to the range, even if it's an indoor range. You might learn a thing or two.