Getting there early is nice, since it gives you your choice of lanes.
Generally, you want one end or the other, because in an end lane you only need to keep an eye out for sloppy gun handling in one direction.
The far right lane is the one least likely to be downrange of bad gun handling: Your average Cletus is right handed, which means that if he lets one fly down the line while trying to puzzle out a type three malf, it's most likely going to his left. On the other hand, if you take the far left lane, you don't get pelted with brass, and any empties that wind up in your range bag will be in a caliber you shoot.
Since getting set on fire by fellow range attendees really isn't all that common when compared with statistically more frequent occurrences, like getting struck by lightning or bear attacks, I'll usually take the far left if I have a choice and pelt others with my brass, rather than being the peltee. I still keep a weather eye out for errant Cletii, though, in much the same way that I wouldn't stand on a hill in Yellowstone under ominous clouds with a metal rod in one hand and a picnic basket in the other.
It's comforting to hear an older shooter off to your right sharply chastise his younger companion "Now, keep that gun pointed downrange the whole time, even when you're reloading! Don't point it across the line!" It's a lot less comforting to hear it for the fourth or seventh time, because by then it's obvious that Cletus Jr. is not picking up on this particular point of firearms etiquette, but what are you gonna do?